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Hashimoto's thyroiditis

The name Hashimoto's thyroiditis comes from the pathologist who in 1912 first described the microscopic features of the disease.

H. Hashimoto: Zur Kenntnis der lymphomatösen Veränderung der Schilddrüse (Struma lymphomatosa). Archiv für klinische Chirurgie, Berlin, 1912, 97: 219-248


Dr. Hakaru Hashimoto was born in May 5, 1881 and died of typhoid fever in January 9, 1934 at the age of 52, unfortunately without receiving

the recognition he merited for his discovery, which would later be called Hashimoto’s disease.

Hashimoto's disease is the most common cause of hypothyroidism in iodine-sufficient areas throughout the world such as the United States. This is called an underactive thyroid or hypothyroidism. Without enough thyroid hormone, many of the body’s functions slow down. When you have Hashimoto's disease, your immune system begins to attack your thyroid gland, causing it to become swollen and irritated. It is an autoimmune disease, which means that the body inappropriately attacks the thyroid gland - as if it was foreign tissue. T lymphocytes, a type of cell involved in the inflammation process, invade the thyroid gland cause silent, painless inflammation that destroys it; ultimately, the individual produces little or no thyroid hormone and becomes hypothyroid. Hashimoto's disease is most common in middle-aged women and tends to run in families. It also is called Hashimoto’s thyroiditis. In general, there is a gradual loss of thyroid function, often accompanied by enlargement of the thyroid gland, also known as a goiter. Hypothyroidism is a disorder that occurs when the thyroid doesn’t make enough thyroid hormone for the body’s needs. Blood drawn from people with Hashimoto's thyroiditis typically reveals an increased number of antibodies against thyroid-specific proteins, including thyroperoxidase and thyroglobulin. An underactive thyroid causes every function of the body to slow down, such as heart rate, brain function, and the rate your body turns food into energy. Hashimoto's thyroiditis tends to occur in families. Hashimoto's thyroiditis is 5 to 10 times more common in women than in men and most often starts in adulthood. It can be associated with other autoimmune conditions such as type 1 diabetes or celiac disease. It is closely related to Graves’ disease, another autoimmune disease affecting the thyroid.